Unraveling Fragile X Syndrome

November 28, 2017

In 1943, Julia Bell and James Martin first described the sex-linked heritable condition now termed Fragile X Syndrome (FXS). In their paper, “A Pedigree of Mental Deficit Showing Sex-Linkage”, they described a single kindred in which eleven males spanning two generations  exhibited mental deficiency. After detailed investigation, the researchers concluded that the condition was ...

Tackling Rotavirus

April 24, 2017

Rotavirus gastroenteritis is the leading cause of diarrhea-associated hospitalizations and death in children younger than 5 years of age. Rotavirus illness is caused by a virus which enters the body by mouth and infects the intestines. It is a particularly hardy and contagious virus, capable of surviving on inanimate surfaces for long periods and spreading readily from child to child and also ...

Congenital Cytomegalovirus Infection and Hearing Loss

March 16, 2017

It has been over 50 years that the association between congenital Cytomegalovirus (CMV)  infection and hearing loss was described by Medearis et al. During that time, advances in understanding the pathogenesis and the natural history of the disease have been made. It is now acknowledged that CMV infection is not only the most common congenital viral infection in the world but also the leading ...

Supporting Universal Antenatal Pertussis Vaccination

July 20, 2016

Pertussis (Whooping Cough) is a serious health issue, especially in the very young infant. It is caused by a bacteria, Bordetella pertussis, and is transmitted person to person via aerosol droplets usually by coughing or sneezing. The illness typically begins with cold-like symptoms which may then progress to the characteristic paroxysms of cough terminating with an inspiratory whoop. In young ...